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Article

Evaluation of CYP2C19, P2Y12, and ABCB1 polymorphisms and phenotypic response to clopidogrel in healthy Indian adults.

Indian journal of pharmacology - 1 Jan 2000

Sridharan Kannan, Kataria Rachna, Tolani Drishti, Bendkhale Shital, Gogtay Nithya J, Thatte Urmila M

Abstract excerpt

INTRODUCTION: CYP2C19 and P2Y12 polymorphisms have been claimed to alter the pharmacodynamic response to clopidogrel. ABCB1 polymorphism has been associated with the efflux of clopidogrel resulting in decreased bioavailability. Due to paucity of data from Indian population, the present study was undertaken to evaluate the association of genetic polymorphisms of CYP2C19, P2Y12, and ABCB1 with inhibition of...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Clopidogrel

Share to Cytochrome P-450 CYP2C19

Share to Platelet Aggregation

Share to Platelet Aggregation Inhibitors

Share to Receptors, Purinergic P2Y12

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Source

Open in PubMed Open full text

Identifiers

PMID: 27756942
DOI: 10.4103/0253-7613.186191
PMCID: PMC4980919

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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