Article
Effects of CYP2C19 loss-of-function variants on the eradication of H. pylori infection in patients treated with proton pump inhibitor-based triple therapy regimens: a meta-analysis of randomized clinical trials.
PloS one - 1 Jan 2013
Tang Hui-Lin, Li Yan, Hu Yong-Fang, Xie Hong-Guang, Zhai Suo-Di
Abstract excerpt
BACKGROUND: There are inconsistent conclusions about whether CYP2C19 variants could affect H. pylori eradication rate in patients treated with the proton pump inhibitor (PPI)-based therapy. We therefore performed a meta-analysis of randomized clinical trials (RCTs) to re-evaluate the impact of CYP2C19 variants on PPI-based triple therapy for the above indication. METHODS: All relevant RCTs in the PubMed, Cochrane...
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