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Article

KCNQ channels regulate age-related memory impairment.

PloS one - 1 Jan 2013

Cavaliere Sonia, Malik Bilal R, Hodge James J L

Abstract excerpt

In humans KCNQ2/3 heteromeric channels form an M-current that acts as a brake on neuronal excitability, with mutations causing a form of epilepsy. The M-current has been shown to be a key regulator of neuronal plasticity underlying associative memory and ethanol response in mammals. Previous work has shown that many of the molecules and plasticity mechanisms underlying changes in alcohol behaviour and addiction...

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Identifiers

PMID: 23638087
DOI: 10.1371/journal.pone.0062445
PMCID: PMC3640075

Genes

KCNQ2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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