Article
KCNQ channels regulate age-related memory impairment.
PloS one - 1 Jan 2013
Cavaliere Sonia, Malik Bilal R, Hodge James J L
Abstract excerpt
In humans KCNQ2/3 heteromeric channels form an M-current that acts as a brake on neuronal excitability, with mutations causing a form of epilepsy. The M-current has been shown to be a key regulator of neuronal plasticity underlying associative memory and ethanol response in mammals. Previous work...
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