Article
Prominin 1/CD133 endothelium sustains growth of proneural glioma.
PloS one - 1 Jan 2013
Ding Bi-Sen, James Daylon, Iyer Rajiv, Falciatori Ilaria, Hambardzumyan Dolores, Wang Su, Butler Jason M, Rabbany Sina Y, Hormigo Adília
Abstract excerpt
In glioblastoma high expression of the CD133 gene, also called Prominin1, is associated with poor prognosis. The PDGF-driven proneural group represents a subset of glioblastoma in which CD133 is not overexpressed. Interestingly, this particular subset shows a relatively good prognosis. As with ma...
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