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Genetic variation in TLR or NFkappaB pathways and the risk of breast cancer: a case-control study.

BMC cancer - 1 May 2013

Resler Alexa J, Malone Kathleen E, Johnson Lisa G, Malkki Mari, Petersdorf Effie W, McKnight Barbara, Madeleine Margaret M

Abstract excerpt

BACKGROUND: Toll-like receptors (TLRs) and the transcription factor nuclear factor-κB (NFκB) are important in inflammation and cancer. METHODS: We examined the association between breast cancer risk and 233 tagging single nucleotide polymorphisms within 31 candidate genes involved in TLR or NFκB pathways. This population-based study in the Seattle area included 845 invasive breast cancer cases, diagnosed between...

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Adaptor Proteins, Signal Transducing
Confidence Intervals
MAP Kinase Kinase Kinase 1
Matrix Metalloproteinase 9
NF-kappa B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Toll-Like Receptor 9

Toll-Like Receptors

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Identifiers

PMID: 23634849
DOI: 10.1186/1471-2407-13-219
PMCID: PMC3651307

Genes

TANK
MMP9
TLR9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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