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Article

Blocking mtDNA replication upregulates the expression of stemness-related genes in prostate cancer cell lines.

Ultrastructural pathology - 1 Aug 2013

Liu Yishan, Wu Xueping, Li Xiaoran, Kvalheim Gunnar, Axcrona Ulrika, Axcrona Karol, Suo Zhenhe

Abstract excerpt

Ethidium bromide (EtBr) is an intercalating agent, which binds tightly to mitochondrial DNA (mtDNA) during replication, and so blocks the function of mitochondria. EtBr inserts itself between the stacked bases in double-stranded DNA and specifically inhibits mtDNA transcription and replication by...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23634795
DOI: 10.3109/01913123.2013.770112

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23634795-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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