Article
Sex differences in the JAK2 V617F allele burden in chronic myeloproliferative disorders.
Haematologica - 1 Jul 2010
Stein Brady L, Williams Donna M, Wang Nae-Yuh, Rogers Ophelia, Isaacs Mary Ann, Pemmaraju Naveen, Spivak Jerry L, Moliterno Alison R
Abstract excerpt
BACKGROUND: The JAK2(V617F) allele burden is a variable measure, determined by the frequency of mitotic recombination events and the expansion of JAK2(V617F) clones. Since variability in the JAK2(V617F) allele burden is partly responsible for the distinct phenotypes seen in the myeloproliferative...
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