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Article

Sex differences in the JAK2 V617F allele burden in chronic myeloproliferative disorders.

Haematologica - 1 Jul 2010

Stein Brady L, Williams Donna M, Wang Nae-Yuh, Rogers Ophelia, Isaacs Mary Ann, Pemmaraju Naveen, Spivak Jerry L, Moliterno Alison R

Abstract excerpt

BACKGROUND: The JAK2(V617F) allele burden is a variable measure, determined by the frequency of mitotic recombination events and the expansion of JAK2(V617F) clones. Since variability in the JAK2(V617F) allele burden is partly responsible for the distinct phenotypes seen in the myeloproliferative disorders, the objective of this study was to identify modifiers of the allele burden. DESIGN AND METHODS: Blood...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20133898
DOI: 10.3324/haematol.2009.014407
PMCID: PMC2895032

Genes

JAK2

Variants

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Source receipt: pubmed, retrieved 7 Sept 2026.

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