Article
Epsilon toxin is essential for the virulence of Clostridium perfringens type D infection in sheep, goats, and mice.
Infection and immunity - 1 Jul 2013
Garcia J P, Adams V, Beingesser J, Hughes M L, Poon R, Lyras D, Hill A, McClane B A, Rood J I, Uzal F A
Abstract excerpt
Clostridium perfringens type D causes disease in sheep, goats, and other ruminants. Type D isolates produce, at minimum, alpha and epsilon (ETX) toxins, but some express up to five different toxins, raising questions about which toxins are necessary for the virulence of these bacteria. We evaluated the contribution of ETX to C. perfringens type D pathogenicity in an intraduodenal challenge model in sheep, goats,...
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