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Towards an Understanding of the Role of <i>Clostridium Perfringens</i> Toxins in Human and Animal Disease

1 Mar 2014

Abstract excerpt

Clostridium perfringens uses its arsenal of >16 toxins to cause histotoxic and intestinal infections in humans and animals. It has been unclear why this bacterium produces so many different toxins, especially since many target the plasma membrane of host cells. However, it is now established that C. perfringens uses chromosomally encoded alpha toxin (a phospholipase C) and perfringolysin O (a pore-forming toxin)...

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PMID: 24762309
DOI: 10.2217/fmb.13.168

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