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Article

Dissecting the contributions of Clostridium perfringens type C toxins to lethality in the mouse intravenous injection model.

Infection and immunity - 1 Sept 2006

Fisher Derek J, Fernandez-Miyakawa Mariano E, Sayeed Sameera, Poon Rachael, Adams Victoria, Rood Julian I, Uzal Francisco A, McClane Bruce A

Abstract excerpt

The gram-positive anaerobe Clostridium perfringens produces a large arsenal of toxins that are responsible for histotoxic and enteric infections, including enterotoxemias, in humans and domestic animals. C. perfringens type C isolates, which cause rapidly fatal diseases in domestic animals and enteritis necroticans in humans, contain the genes for alpha toxin (plc), perfringolysin O (pfoA), beta toxin (cpb), and...

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Identifiers

PMID: 16926413
DOI: 10.1128/IAI.00534-06
PMCID: PMC1594841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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