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Article

Suppression of mitochondrial complex I influences cell metastatic properties.

PloS one - 1 Jan 2013

He Xuelian, Zhou Aifen, Lu Hao, Chen Yong, Huang Guochang, Yue Xin, Zhao Peiwei, Wu Yanxiang

Abstract excerpt

Despite the fact that mitochondrial dysfunction has an important role in tumorigenesis and metastasis, the underlying mechanism remains to be elucidated. Mitochondrial Complex I (NADH:ubiquinone oxidoreductase) is the first and the largest protein complex of the mitochondrial electron-transport chain (ETC),which has an essential role in maintaining mitochondrial function and integrity. In this study, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23630608
DOI: 10.1371/journal.pone.0061677
PMCID: PMC3632579

Genes

NDUFS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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