Article
Heritability of subcortical volumetric traits in mesial temporal lobe epilepsy.
PloS one - 1 Jan 2013
Alhusaini Saud, Scanlon Cathy, Ronan Lisa, Maguire Sinead, Meaney James F, Fagan Andrew J, Boyle Gerard, Borgulya Gabor, Iyer Parameswaran M, Brennan Paul, Costello Daniel, Chaila Elijah, Fitzsimons Mary, Doherty Colin P, Delanty Norman, Cavalleri Gianpiero L
Abstract excerpt
OBJECTIVES: We aimed to 1) determine if subcortical volume deficits are common to mesial temporal lobe epilepsy (MTLE) patients and their unaffected siblings 2) assess the suitability of subcortical volumetric traits as endophenotypes for MTLE. METHODS: MRI-based volume measurements of the hippocampus, amygdala, thalamus, caudate, putamen and pallidium were generated using an automated brain reconstruction method...
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