Article
Hippocampal atrophy and T2-weighted signal changes in familial mesial temporal lobe epilepsy.
Neurology - 11 Feb 2003
Kobayashi E, D'Agostino M D, Lopes-Cendes I, Berkovic S F, Li M L, Andermann E, Andermann F, Cendes F
Abstract excerpt
OBJECTIVE: To correlate the clinical phenotype with hippocampal volumes (HcVs) and signal changes in patients with familial mesial temporal lobe epilepsy (FMTLE). METHODS: FMTLE was defined when at least two first-degree relatives in a family had a clinical-EEG diagnosis of MTLE. Hippocampal formation measurements were performed using 1- to 3-mm coronal T1-weighted MRIs. The presence of hyperintense T2 signal was...
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