Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IGF-I generation test in prepubertal children with Noonan syndrome due to mutations in the PTPN11 gene.

Hormones (Athens, Greece) - 1 Jan 2000

Bertelloni Silvano, Baroncelli Giampiero I, Dati Eleonora, Ghione Silvia, Baldinotti Fulvia, Toschi Benedetta, Simi Paolo

Abstract excerpt

BACKGROUND: Short stature represents one of the main features of children with Noonan syndrome. The reason for impaired growth remains largely unknown. OBJECTIVE: To assess GH and IGF1 secretion in children with Noonan syndrome. PATIENTS: 12 prepubertal children with Noonan syndrome due to mutations in the PTPN11 gene [7 males, 6 females; median age, years: 8.6 (range 5.1-13.4)] were studied; 12 prepubertal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Height
Share to Human Growth Hormone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor I

Share to Noonan Syndrome

Share to Predictive Value of Tests

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 11

Share to Sexual Development

Share to Up-Regulation

Source

Identifiers

PMID: 23624134
DOI: 10.1007/BF03401289

Genes

IGF1
PTPN11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IGF-I generation test in prepubertal children with Noonan syndrome due to mutations in the PTPN11 gene.PMID 23624134Read ↗

Efficacy and safety of growth hormone therapy in children with Noonan syndrome.Semantic proximity Read ↗

PTPN11 (protein tyrosine phosphatase, nonreceptor type 11) mutations and response to growth hormone therapy in children with Noonan syndrome.Semantic proximity Read ↗

Response to growth hormone in short children with Noonan syndrome: correlation to genotype.Semantic proximity Read ↗

Noonan syndrome: relationships between genotype, growth, and growth factors.Semantic proximity Read ↗

Noonan syndrome, the Ras-MAPK signalling pathway and short stature.Semantic proximity Read ↗

[Noonan syndrome: from phenotype to growth hormone therapy].Semantic proximity Read ↗

Comparison of Bioinactive Growth Hormone Cases with Small for Gestational Age and Idiopathic Short Stature CasesSemantic proximity Read ↗

GH therapy in Noonan syndrome: Review of final height data.Semantic proximity Read ↗

Abnormal GH Receptor Signaling in Children with Idiopathic Short StatureSemantic proximity Read ↗

Abnormal growth in noonan syndrome: the challenge of optimal therapy.Semantic proximity Read ↗

Abnormal growth in noonan syndrome: genetic and endocrine features and optimal treatment.Semantic proximity Read ↗

Recombinant Insulin-Like Growth Factor (IGF)-I Treatment in Short Children with Low IGF-I Levels: First-Year Results from a Randomized Clinical TrialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.