Article
Efficacy and safety of growth hormone therapy in children with Noonan syndrome.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Jan 2000
Sodero Giorgio, Cipolla Clelia, Pane Lucia Celeste, Sessa Linda, Malavolta Elena, Arzilli Federica, Leoni Chiara, Zampino Giuseppe, Rigante Donato
Abstract excerpt
Patients with Noonan syndrome typically have a target height <2 standard deviations compared to the general population, and half of the affected adults remain permanently below the 3rd centile for height, though their short stature might result from a multifactorial etiology, not-yet fully understood. The secretion of growth hormone (GH) following the classic GH stimulation tests is often normal, with baseline...
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