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Article

MicroRNA cluster miR-17-92 regulates neural stem cell expansion and transition to intermediate progenitors in the developing mouse neocortex.

Cell reports - 30 May 2013

Bian Shan, Hong Janet, Li Qingsong, Schebelle Laura, Pollock Andrew, Knauss Jennifer L, Garg Vidur, Sun Tao

Abstract excerpt

During development of the embryonic neocortex, tightly regulated expansion of neural stem cells (NSCs) and their transition to intermediate progenitors (IPs) are critical for normal cortical formation and function. Molecular mechanisms that regulate NSC expansion and transition remain unclear. Here, we demonstrate that the microRNA (miRNA) miR-17-92 cluster is required for maintaining proper populations of...

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Identifiers

PMID: 23623502
DOI: 10.1016/j.celrep.2013.03.037
PMCID: PMC3762321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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