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Article

Optimal complement-mediated phagocytosis of Pseudomonas aeruginosa by monocytes is cystic fibrosis transmembrane conductance regulator-dependent.

American journal of respiratory cell and molecular biology - 1 Sept 2013

Van de Weert-van Leeuwen Pauline B, Van Meegen Marit A, Speirs Jennifer J, Pals D J, Rooijakkers Suzan H M, Van der Ent Cornelis K, Terheggen-Lagro Suzanne W J, Arets Hubertus G M, Beekman Jeffrey M

Abstract excerpt

Cystic fibrosis (CF) is caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and is characterized by chronic pulmonary infections. The mechanisms underlying chronic infection and inflammation remain incompletely understood. Mutant CFTR in nonepithelial tissues such as immune cells has been suggested to contribute to infection, inflammation, and the resultant lung disease....

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Source

Identifiers

PMID: 23617438
DOI: 10.1165/rcmb.2012-0502OC

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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