Article
Mechanisms of cognitive impairment in cerebral small vessel disease: multimodal MRI results from the St George's cognition and neuroimaging in stroke (SCANS) study.
PloS one - 1 Jan 2013
Lawrence Andrew J, Patel Bhavini, Morris Robin G, MacKinnon Andrew D, Rich Philip M, Barrick Thomas R, Markus Hugh S
Abstract excerpt
Cerebral small vessel disease (SVD) is a common cause of vascular cognitive impairment. A number of disease features can be assessed on MRI including lacunar infarcts, T2 lesion volume, brain atrophy, and cerebral microbleeds. In addition, diffusion tensor imaging (DTI) is sensitive to disruption of white matter ultrastructure, and recently it has been suggested that additional information on the pattern of...
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