Article
Catechol-O-methyltransferase Val158Met polymorphism and risk of autism spectrum disorders.
The Journal of international medical research - 1 Jun 2013
Guo Tianyou, Wang Weiqian, Liu Bing, Chen Hong, Yang Chuang
Abstract excerpt
OBJECTIVE: Autism spectrum disorders (ASD) are a family of childhood-onset neurodevelopmental disorders with complex genetic mechanisms underlying their aetiology. The aim of this case-control study was to evaluate the effect of the catechol-O-methyltransferase (COMT) gene Val158Met polymorphism on ASD risk in a Chinese Han population. METHODS: The COMT gene Val158Met polymorphism was detected by polymerase chain...
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