Article
Norepinephrine genes predict response time variability and methylphenidate-induced changes in neuropsychological function in attention deficit hyperactivity disorder.
Journal of clinical psychopharmacology - 1 Jun 2013
Kim Bung-Nyun, Kim Jae-Won, Cummins Tarrant D R, Bellgrove Mark A, Hawi Ziarih, Hong Soon-Beom, Yang Young-Hui, Kim Hyo-Jin, Shin Min-Sup, Cho Soo-Churl, Kim Ji-Hoon, Son Jung-Woo, Shin Yun-Mi, Chung Un-Sun, Han Doug-Hyun
Abstract excerpt
Noradrenergic dysfunction may be associated with cognitive impairments in attention-deficit/hyperactivity disorder (ADHD), including increased response time variability, which has been proposed as a leading endophenotype for ADHD. The aim of this study was to examine the relationship between polymorphisms in the α-2A-adrenergic receptor (ADRA2A) and norepinephrine transporter (SLC6A2) genes and attentional...
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