Article
Adrenergic α2A receptor gene is not associated with methylphenidate response in adults with ADHD.
European archives of psychiatry and clinical neuroscience - 1 Apr 2011
Contini Verônica, Victor Marcelo M, Cerqueira Caio C S, Polina Evelise R, Grevet Eugênio H, Salgado Carlos A I, Karam Rafael G, Vitola Eduardo S, Belmonte-de-Abreu Paulo, Bau Claiton H D
Abstract excerpt
Adrenergic α2A receptor gene (ADRA2A) is one of the most promising candidate genes for ADHD pharmacogenetics. Thus far, three studies have investigated the association between the ADRA2A -1291 C>G polymorphism and the therapeutic response to methylphenidate (MPH) in children with ADHD, all of them with positive results. The aim of this study is to investigate, for the first time, the association between three...
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