Article
Lack of evidence of human papillomavirus-induced squamous cell carcinomas of the oral cavity in southern Germany.
Oral oncology - 1 Sept 2013
Reuschenbach Miriam, Kansy Katinka, Garbe Kira, Vinokurova Svetlana, Flechtenmacher Christa, Toth Csaba, Prigge Elena-Sophie, Thiele Oliver C, Reinert Siegmar, Hoffmann Jürgen, von Knebel Doeberitz Magnus, Freier Kolja
Abstract excerpt
OBJECTIVES: The aim of the present study was to identify HPV-attributable SCC of the oral cavity (OSCC) in a cohort of patients from southern Germany. MATERIALS AND METHODS: A sensitive PCR-enzyme immunoassay (EIA) was followed by a more specific in situ hybridization (ISH) to detect high risk human papillomavirus (HPV). An immunohistochemical dual-staining for p16(INK4a) and the proliferation marker Ki-67 was...
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