Article
Low prevalence of HPV-driven head and neck squamous cell carcinoma in North-East Italy.
Papillomavirus research (Amsterdam, Netherlands) - 1 Dec 2016
Baboci Lorena, Holzinger Dana, Boscolo-Rizzo Paolo, Tirelli Giancarlo, Spinato Roberto, Lupato Valentina, Fuson Roberto, Schmitt Markus, Michel Angelika, Halec Gordana, Da Mosto Maria Cristina, Pawlita Michael, Del Mistro Annarosa
Abstract excerpt
OBJECTIVES: To investigate the frequency of Human papillomavirus (HPV)-driven head and neck squamous cell carcinoma (HNSCC) among patients living in North-East Italy, by assessing HPV-DNA positivity in all tumors and additional markers whenever possible. MATERIAL AND METHODS: HPV types, viral load, viral RNA, HPV16/18 E6 protein and p16INK4a and pRb expression were determined in primary tumor tissues from 247...
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