C1q but not mannose-binding lectin (Mbl-2) gene polymorphisms are associated with type 2 diabetes in the genetically homogeneous population of the island of Crete in Greece.

doi:10.1016/j.humimm.2013.04.003

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Article

C1q but not mannose-binding lectin (Mbl-2) gene polymorphisms are associated with type 2 diabetes in the genetically homogeneous population of the island of Crete in Greece.

Human immunology - 1 Jul 2013

Goulielmos George N, Samonis George, Apergi Marina, Christofaki Maria, Valachis Antonis, Zervou Maria I, Kofteridis Diamantis P

Abstract excerpt

AIM: To investigate the role of mannose-binding lectin 2 (MBL2) and C1q gene polymorphisms on the susceptibility to type 2 diabetes (T2D), that may contribute to increased risk of infections in the genetically homogeneous Greek population of the island of Crete. METHODS: Ninety five patients with T2D and 333 healthy controls, all local Cretans were genotyped for the MBL-2 rs11003125 (C>G) and C1q rs292001 (G>A)...

Topics

Aged
Aged, 80 and over
Complement C1q
DNA Mutational Analysis
Diabetes Mellitus, Type 2
Female
Gene Frequency
Genetic Association Studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Genotype

Greece

Humans

Male

Mannose-Binding Lectin

Middle Aged

Polymorphism, Single Nucleotide

Population Groups

Source

Open in PubMed

Identifiers

PMID: 23602874
DOI: 10.1016/j.humimm.2013.04.003

Genes

MBL2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.