Article
Interaction of KIR genes and G1M immunoglobulin allotypes confer susceptibility to type 2 diabetes in Puerto Rican Americans.
Human immunology - 1 Nov 2006
Zuniga Joaquin, Romero Viviana, Azocar Jose, Stern Joel N H, Clavijo Olga, Almeciga Ingrid, Encinales Liliana, Avendano Angel, Fridkis-Hareli Masha, Pandey Janardan P, Yunis Edmond J
Abstract excerpt
The susceptibility to type 2 diabetes (T2D) involves genetic factors. We studied the distribution of KIR and MHC class I ligands phenotype and genotype frequencies, as well as immunoglobulin KM and GM allotype frequencies in a group of patients (N = 95) with T2D and ethnically matched healthy controls (N = 74) with Puerto Rican ethnic background. We found a slight increase of the 2DL3/2DL3 homozygous genotype in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.