Article
Intron 4 a/b polymorphism of the endothelial nitric oxide synthase gene is associated with both type 1 and type 2 diabetes in a genetically homogeneous population.
Human immunology - 1 Jan 2000
Galanakis Emmanouil, Kofteridis Diamantis, Stratigi Kalliopi, Petraki Eleni, Vazgiourakis Vassilios, Fragouli Eleni, Mamoulakis Dimitrios, Boumpas Dimitrios T, Goulielmos George N
Abstract excerpt
Current classifications of diabetes distinguish between type 1 diabetes (T1D) and type 2 diabetes (T2D), however recent evidence highlights overlap between T1D and T2D. Earlier studies have suggested altered nitric oxide (NO) metabolism in both T1D and T2D. In the present case-control study, we investigated whether the endothelial NO synthase gene intron 4 a/b polymorphism is associated with T1D and T2D in the...
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