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Article

IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer

18 Apr 2013

Abstract excerpt

Copy number alterations are frequently found in colorectal cancer (CRC), and recurrent gains or losses are likely to correspond to regions harbouring genes that promote or impede carcinogenesis respectively. Gain of chromosome 13q is common in CRC but, because the region of gain is frequently large, identification of the driver gene(s) has hitherto proved difficult. We used array comparative genomic hybridization...

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PMID: 23594372
DOI: 10.1111/iep.12021

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