Article
Inverse relationship between viral load and genotypic resistance mutations in Korean patients with primary HIV type 1 infections.
AIDS research and human retroviruses - 1 Nov 2006
Chin Bum Sik, Choi Juyeon, Nam Jeong-Gu, Kee Mee Kyung, Suh Soon Deok, Choi Jin Young, Chu Chaeshin, Kim Sung Soon
Abstract excerpt
The transmission of antiretroviral-resistant HIV-1 strains is associated with suboptimal virological responses to initial antiretroviral therapy. However, certain types of resistance mutations are known to be associated with decreased viral fitness, which confers a lower replication capacity than that of the wild-type virus in the absence of antiretroviral drugs. Therefore, we evaluated the relationship between...
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