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Article

The effect of hydroxcarbamide therapy on survival of children with sickle cell disease.

British journal of haematology - 1 Jun 2013

Lobo Clarisse Lopes de Castro, Pinto Jorge F C, Nascimento Emilia M, Moura Patricia G, Cardoso Gilberto P, Hankins Jane S

Abstract excerpt

Although evidence is accumulating that hydroxycarbamide decreases mortality among adults with sickle cell disease (SCD), there are no published data regarding the effect of hydroxycarbamide on mortality among children. The Paediatric Hydroxycarbamide Program was established to treat children with SCD aged 3-18 years if they met disease severity criteria. Mortality data and clinical/laboratorial effects of...

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Topics

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Share to Adolescent
Share to Anemia, Sickle Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Child, Preschool

Share to Hemoglobin, Sickle

Share to Hydroxyurea

Share to Treatment Outcome

Source

Identifiers

PMID: 23590693
DOI: 10.1111/bjh.12323

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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