Article
Epidermal growth factor receptor mutations in non- small cell lung cancers in a multiethnic malaysian patient population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Liam Chong-Kin, Leow Hwong-Ruey, How Soon-Hin, Pang Yong-Kek, Chua Keong-Tiong, Lim Boon-Khaw, Lai Nai-Lang, Kuan Yeh-Chunn, Pailoor Jayalakshmi, Rajadurai Pathmanathan
Abstract excerpt
BACKGROUND: Mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) in non- small cell lung cancer (NSCLC) are predictive of response to EGFR-targeted therapy in advanced stages of disease. This study aimed to determine the frequency of EGFR mutations in NSCLCs and to correlate their presence with clinical characteristics in multiethnic Malaysian patients. MATERIALS AND METHODS: In...
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