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Article

Inducible re-expression of HEXIM1 causes physiological cardiac hypertrophy in the adult mouse.

Cardiovascular research - 1 Jul 2013

Montano Monica M, Desjardins Candida L, Doughman Yong Qui, Hsieh Yee-Hsee, Hu Yanduan, Bensinger Heather M, Wang Connie, Stelzer Julian E, Dick Thomas E, Hoit Brian D, Chandler Margaret P, Yu Xin, Watanabe Michiko

Abstract excerpt

AIMS: The transcription factor hexamethylene-bis-acetamide-inducible protein 1 (HEXIM1) regulates myocardial vascularization and growth during cardiogenesis. Our aim was to determine whether HEXIM1 also has a beneficial role in modulating vascularization, myocardial growth, and function within the adult heart. METHODS AND RESULTS: To achieve our objective, we created and investigated a mouse line wherein HEXIM1...

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Source

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Identifiers

PMID: 23585471
DOI: 10.1093/cvr/cvt086
PMCID: PMC3687752

Genes

HEXIM1
GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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