Article
Genome engineering in actinomycetes using site-specific recombinases.
Applied microbiology and biotechnology - 1 Jun 2013
Myronovskyi Maksym, Luzhetskyy Andriy
Abstract excerpt
The rational modification of the actinomycetes genomes has a variety of applications in research, medicine, and biotechnology. The use of site-specific recombinases allows generation of multiple mutations, large DNA deletions, integrations, and inversions and may lead to significant progress in all of these fields. Despite their huge potential, site-specific recombinase-based technologies have primarily been used...
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