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Article

Genetically proxied IL-6 receptor inhibition is associated with increased risk of atopic dermatitis.

The Journal of allergy and clinical immunology - 1 Sept 2024

Zhao Sizheng Steven, Yiu Zenas Z N

Abstract excerpt

BACKGROUND: Dermatitis has been reported after initiation of IL-6 receptor (IL-6R) inhibitors (IL-6Ri), while genetic association studies of atopic dermatitis (AD) have implicated IL-6R pathway signaling. However, causality remains unclear. As the indications for IL-6Ri expand, so do the clinical importance of determining whether there is mechanistic evidence linking it to AD. OBJECTIVE: Our aim was to examine...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Receptors, Interleukin-6

Source

Identifiers

PMID: 38801923
DOI: 10.1016/j.jaci.2024.05.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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