Article
The role of memory-related gene WWC1 (KIBRA) in lifetime posttraumatic stress disorder: evidence from two independent samples from African conflict regions.
Biological psychiatry - 1 Nov 2013
Wilker Sarah, Kolassa Stephan, Vogler Christian, Lingenfelder Birke, Elbert Thomas, Papassotiropoulos Andreas, de Quervain Dominique J-F, Kolassa Iris-Tatjana
Abstract excerpt
BACKGROUND: Posttraumatic stress disorder (PTSD) results from the formation of a strong memory for the sensory-perceptual and affective representations of traumatic experiences, which is detached from the corresponding autobiographical context information. Because WWC1, the gene encoding protein KIBRA, is associated with long-term memory performance, we hypothesized that common WWC1 alleles influence the risk for...
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