Article
Birbeck granule-like "organized smooth endoplasmic reticulum" resulting from the expression of a cytoplasmic YFP-tagged langerin.
PloS one - 1 Jan 2013
Lenormand Cédric, Spiegelhalter Coralie, Cinquin Bertrand, Bardin Sabine, Bausinger Huguette, Angénieux Catherine, Eckly Anita, Proamer Fabienne, Wall David, Lich Ben, Tourne Sylvie, Hanau Daniel, Schwab Yannick, Salamero Jean, de la Salle Henri
Abstract excerpt
Langerin is required for the biogenesis of Birbeck granules (BGs), the characteristic organelles of Langerhans cells. We previously used a Langerin-YFP fusion protein having a C-terminal luminal YFP tag to dynamically decipher the molecular and cellular processes which accompany the traffic of Langerin. In order to elucidate the interactions of Langerin with its trafficking effectors and their structural impact...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.