Article
hOGG1 Ser326Cys polymorphism and risk of hepatocellular carcinoma among East Asians: a meta-analysis.
PloS one - 1 Jan 2013
Wang Wenjun, Dang Shuangsuo, Li Yaping, Sun Mingzhu, Jia Xiaoli, Wang Rui, Liu Jingkun
Abstract excerpt
BACKGROUND: The hOGG1 gene encodes a DNA glycosylase enzyme responsible for DNA repair. The Ser326Cys polymorphism in this gene may influence its repair ability and thus plays a role in carcinogenesis. Several case-control studies have been conducted on this polymorphism and its relationship with the risk of hepatocellular carcinoma (HCC) among East Asians. However, their results are inconsistent. METHODS: We...
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