Article
A herpes simplex virus scaffold peptide that binds the portal vertex inhibits early steps in viral replication.
Journal of virology - 1 Jun 2013
Yang Kui, Wills Elizabeth, Baines Joel D
Abstract excerpt
Previous experiments identified a 12-amino-acid (aa) peptide that was sufficient to interact with the herpes simplex virus 1 (HSV-1) portal protein and was necessary to incorporate the portal into capsids. In the present study, cells were treated at various times postinfection with peptides consisting of a portion of the Drosophila antennapedia protein, previously shown to enter cells efficiently, fused to either...
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