Article
An<i>in vitro</i>expansion score for tissue-engineering applications with human bone marrow-derived mesenchymal stem cells
10 Apr 2013
Abstract excerpt
Human bone marrow-derived mesenchymal stem cells (MSCs) have limited growth potential in vitro and cease to divide due to replicative senescence, which from a tissue-engineering perspective has practical implications, such as defining the correct starting points for differentiation and transplantation. Time spent in culture before the loss of required differentiation potential is different and reflects patient...
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