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Viral Infections: Negative Regulators of Apoptosis and Oncogenic Factors

1 Oct 2020

Abstract excerpt

The disruption of apoptotic cell death process is closely associated with the etiology of various diseases, including cancer. Permanent viral infections can cause different types of cancers. Oncogenic viruses manipulate both external and internal apoptosis pathways, and inhibit the activity of proapoptotic proteins and signaling pathways, which facilitates carcinogenesis. Ineffective immune surveillance or immune...

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PMID: 33202204
DOI: 10.1134/s0006297920100077

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