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Article

Contribution of selected gene mutations to resistance in clinical isolates of vancomycin-intermediate Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Nov 2012

Hafer Cory, Lin Ying, Kornblum John, Lowy Franklin D, Uhlemann Anne-Catrin

Abstract excerpt

Infections with vancomycin-intermediate Staphylococcus aureus (VISA) have been associated with vancomycin treatment failures and poor clinical outcomes. Routine identification of clinical isolates with increased vancomycin MICs remains challenging, and no molecular marker exists to aid in diagnosis of VISA strains. We tested vancomycin susceptibilities by using microscan, Etest, and population analyses in a...

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Identifiers

PMID: 22948864
DOI: 10.1128/AAC.01139-12
PMCID: PMC3486570

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