Article
The cyclin D1 (CCND1) rs9344 G>A polymorphism predicts clinical outcome in colon cancer patients treated with adjuvant 5-FU-based chemotherapy.
The pharmacogenomics journal - 1 Apr 2014
Absenger G, Benhaim L, Szkandera J, Zhang W, Yang D, Labonte M J, Pichler M, Stotz M, Samonigg H, Renner W, Gerger A, Lenz H-J
Abstract excerpt
Recent evidence indicates a potential prognostic and predictive value for germline polymorphisms in genes involved in cell cycle control. We investigated the effect of cyclin D1 (CCND1) rs9344 G>A in stage II/III colon cancer patients and validated the findings in an independent study cohort. For...
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