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Article

Dissecting the kinetics of the NADP(+)-FADH2 charge transfer complex and flavin semiquinones in neuronal nitric oxide synthase.

Journal of inorganic biochemistry - 1 Jul 2013

Li Huiying, Jamal Joumana, Chreifi Georges, Venkatesh Vikram, Abou-Ziab Hoda, Poulos Thomas L

Abstract excerpt

Electron flow within the neuronal nitric oxide synthase reductase domain (nNOSrd) includes hydride transfer from NADPH to FAD followed by two one-electron transfer reactions from FAD to FMN. We have used stopped flow spectrometry to closely monitor these electron transfer steps for both the wild type and the ΔG810 mutant of nNOSrd using a protocol involving both global analyses of the photodiode array spectral...

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Identifiers

PMID: 23567464
DOI: 10.1016/j.jinorgbio.2013.03.008
PMCID: PMC3716911

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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