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Article

Rapid detection of SNP (c.309T>G) in the MDM2 gene by the Duplex SmartAmp method.

PloS one - 1 Jan 2013

Enokida Yasuaki, Shimizu Kimihiro, Atsumi Jun, Lezhava Alexander, Tanaka Yuki, Kimura Yasumasa, Soma Takahiro, Hanami Takeshi, Kawai Yuki, Usui Kengo, Okano Yasuko, Kakegawa Seiichi, Ogawa Hiroomi, Miyamae Yohei, Miyagi Yohei, Nakayama Haruhiko, Ishikawa Toshihisa, Hayashizaki Yoshihide, Takeyoshi Izumi

Abstract excerpt

BACKGROUND: Genetic polymorphisms in the human MDM2 gene are suggested to be a tumor susceptibility marker and a prognostic factor for cancer. It has been reported that a single nucleotide polymorphism (SNP) c.309T>G in the MDM2 gene attenuates the tumor suppressor activity of p53 and accelerates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23565197
DOI: 10.1371/journal.pone.0060151
PMCID: PMC3614994

Genes

MDM2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23565197-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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