The alpaca agouti gene: genomic locus, transcripts and causative mutations of eumelanic and pheomelanic coat color.

doi:10.1016/j.gene.2013.03.060

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Article

The alpaca agouti gene: genomic locus, transcripts and causative mutations of eumelanic and pheomelanic coat color.

Gene - 1 Jun 2013

Chandramohan Bathrachalam, Renieri Carlo, La Manna Vincenzo, La Terza Antonietta

Abstract excerpt

The agouti gene encodes the agouti signaling protein (ASIP) which regulates pheomelanin and eumelanin synthesis in mammals. To investigate the role of agouti in coat color variation of alpaca, we characterized the agouti gene and identified three mutations potentially involved with the determinism of eumelanic and pheomelanic phenotypes. The exon-4 hosts the mutations g.3836C>T, g.3896G>A and g.3866_3923del57....

Topics

5' Untranslated Regions
Agouti Signaling Protein
Amino Acid Sequence
Animals
Base Sequence
Camelids, New World
Color
Exons
Genetic Loci
Genotype
Melanins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Phenotype

RNA, Messenger

Sequence Alignment

Skin

Source

Open in PubMed

Identifiers

PMID: 23558248
DOI: 10.1016/j.gene.2013.03.060

Genes

ASIP
NCOA6

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