Article
A polymorphism in the agouti signalling protein (ASIP) is associated with decreased levels of mRNA.
Pigment cell research - 1 Jun 2006
Voisey J, Gomez-Cabrera M Del C, Smit D J, Leonard J H, Sturm R A, van Daal A
Abstract excerpt
To date, a role for agouti signalling protein (ASIP) in human pigmentation has not been well characterized. It is known that agouti plays a pivotal role in the pigment switch from the dark eumelanin to the light pheomelanin in the mouse. However, because humans do not have an agouti banded hair pattern, its role in human pigmentation has been questioned. We previously identified a single polymorphism in the...
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