Article
Retinal ganglion cell numbers and delayed retinal ganglion cell death in the P23H rat retina.
Experimental eye research - 1 Dec 2010
García-Ayuso Diego, Salinas-Navarro Manuel, Agudo Marta, Cuenca Nicolás, Pinilla Isabel, Vidal-Sanz Manuel, Villegas-Pérez María P
Abstract excerpt
The P23H-1 rat strain carries a rhodopsin mutation frequently found in retinitis pigmentosa patients. We investigated the progressive degeneration of the inner retina in this strain, focussing on retinal ganglion cells (RGCs) fate. Our data show that photoreceptor death commences in the ventral r...
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