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Genome-Wide Analysis of Host mRNA Translation during Hepatitis C Virus Infection

4 Apr 2013

Abstract excerpt

In the model of Huh-7.5.1 hepatocyte cells infected by the JFH1 hepatitis C virus (HCV) strain, transcriptomic and proteomic studies have revealed modulations of pathways governing mainly apoptosis and cell cycling. Differences between transcriptomic and proteomic studies pointed to regulations occurring at the posttranscriptional level, including the control of mRNA translation. In this study, we investigated at...

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PMID: 23552407
DOI: 10.1128/jvi.00538-13

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