Article
The systemic cytokine environment is permanently altered in multiple myeloma.
PloS one - 1 Jan 2013
Zheng Mary M, Zhang Zhifang, Bemis Kyle, Belch Andrew R, Pilarski Linda M, Shively John E, Kirshner Julia
Abstract excerpt
Multiple myeloma (MM) is an incurable bone marrow malignancy of the B cell lineage. Utilizing multiplex Luminex technology we measured levels of 25 cytokines in the plasma of normal donors (n = 177), those with monoclonal gammopathy of undetermined significance (n = 8), and MM patients (n = 55) with either active disease, on treatment, or in remission. The cytokine levels were compared between normal donors and...
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