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Article

A gene expression inflammatory signature specifically predicts multiple myeloma evolution and patients survival

16 Dec 2016

Abstract excerpt

Multiple myeloma (MM) is closely dependent on cross-talk between malignant plasma cells and cellular components of the inflammatory/immunosuppressive bone marrow milieu, which promotes disease progression, drug resistance, neo-angiogenesis, bone destruction and immune-impairment. We investigated the relevance of inflammatory genes in predicting disease evolution and patient survival. A bioinformatics study by...

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PMID: 27983725
DOI: 10.1038/bcj.2016.118

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