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Article

A novel role for autophagy in neurodevelopment.

Autophagy - 1 Jan 2000

Cecconi Francesco, Di Bartolomeo Sabrina, Nardacci Roberta, Fuoco Claudia, Corazzari Marco, Giunta Luigi, Romagnoli Alessandra, Stoykova Anastassia, Chowdhury Kamal, Fimia Gian Maria, Piacentini Mauro

Abstract excerpt

We recently showed that Ambra 1, a WD40-containing approximately 130 KDa protein, is a novel activating molecule in Beclin 1-regulated autophagy and plays a role in the development of the nervous system. Ambra 1 binds to Beclin 1 and favors Beclin 1/Vps34 interaction. At variance with these facto...

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Identifiers

PMID: 17622796
DOI: 10.4161/auto.4616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17622796-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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